US20110165626A1 – High Yield Production of Sialic Acid (Neu5ac) by Fermentation – Google Patents
Neu5Ac used to be purified from animal sources such as edible bird’s nest (Martin et al., 1977) or egg yolk (Koketsu et al., 1992). However the low sialic acid content of these materials resulted in a low overall production yield and precluded the development of an economically practical industrial process. Glycosidically bound, but not free, …